The brain maps relationships across three neural dimensions—space, time, and closeness—and losing someone requires remapping these circuits. Grief differs fundamentally from depression; it involves yearning driven by oxytocin and disrupted predictions about where and when someone will appear. Science-based tools like dedicated grieving blocks, sleep optimization, and vagal tone training help move through grief adaptively without dismantling attachment. The inferior parietal lobule maps all relationships using three dimensions: physical space, time, and emotional closeness, which must be remapped after loss to uncouple attachment from episodic memories.