Fluoride toothpaste, antiseptic mouthwash, and antacids may be reversing the cardiovascular benefits of exercise by destroying your oral microbiome and blocking nitric oxide production—affecting 2 in 3 Americans with high blood pressure. Dr. Nathan Bryan explains how everyday oral hygiene habits sabotage blood vessel function, hormone activation, and wound healing. Using mouthwash eliminates the cardioprotective benefits of exercise by killing the oral microbiome bacteria responsible for nitric oxide production. Fluoride in toothpaste is neurotoxic, lowering IQ by up to 7 points in children and shutting down thyroid function, yet most people apply 10-20 times the recommended pea-sized amount.